TIAM1 antibody, TIAM-1 antibody, TIAM 1 antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OST00086G

$240USD

ID Tag

Rb330-200308-G

Immunogen

A synthetic peptide from human T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1, TIAM1) conjugated to blue carrier protein was used as the antigen.

Accession

TIAM1_HUMAN
TIAM1_MOUSE

Also known

TIAM-1, TIAM1

Target

FUNCTION: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.
SUBUNIT: Interacts with BAIAP2.
TISSUE SPECIFICITY: Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Habets G.G.M, et al. Oncogene 10:1371-1376(1995).

Limitation

For research use only