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Code
OSA00051W
$240USD
ID Tag
Rb1713-021210-W
Immunogen
A synthetic peptide from aa region 3223-3250 of mouse ALMS1 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
ALMS1
Target
FUNCTION: Possible role in intracellular trafficking.
SUBCELLULAR LOCATION: Cytoplasm. Centrosome. Cell projection, cilium basal body. Note: Associated with centrosomes and basal body at the base of primary cilia. During mitosis localizes to both spindle poles.
TISSUE SPECIFICITY: Ubiquitously expressed.
DEVELOPMENTAL STAGE: Expressed at E7.5. At E8.0 expression is found in mesodermal- and ectodermal-derived layers. At E10.5 mainly detected in midbrain, hindbrain, forelimb and hindlimb. Also expressed at E15.5 and E18.5.
MISCELLANEOUS: Mice lacking Alms1 display obesity, hypogonadism, hyperinsulinemia, retinal dysfunction and hearing loss.
SUBCELLULAR LOCATION: Cytoplasm. Centrosome. Cell projection, cilium basal body. Note: Associated with centrosomes and basal body at the base of primary cilia. During mitosis localizes to both spindle poles.
TISSUE SPECIFICITY: Ubiquitously expressed.
DEVELOPMENTAL STAGE: Expressed at E7.5. At E8.0 expression is found in mesodermal- and ectodermal-derived layers. At E10.5 mainly detected in midbrain, hindbrain, forelimb and hindlimb. Also expressed at E15.5 and E18.5.
MISCELLANEOUS: Mice lacking Alms1 display obesity, hypogonadism, hyperinsulinemia, retinal dysfunction and hearing loss.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Collin G.B, et al. Nat. Genet. 31:74-78(2002).
2. Dai J, et al. J. Proteome Res. 6:250-262(2007).
2. Dai J, et al. J. Proteome Res. 6:250-262(2007).
Limitation
For research use only
Code
OSA00051W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for ALMS1.
Spcs X-react.
Mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSA00051W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to ALMS1 (3223-3250)
