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Code
OSS00048G
$240USD
ID Tag
Rb326-200308-G
Immunogen
A synthetic peptide from aa region 2-50 of human SEC22b conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Accession
Also known
SEC22 vesicle-trafficking protein homolog B, SEC22 vesicle-trafficking protein-like 1, ERS24, ERS-24, Vesicle-trafficking protein SEC22b, SEC22L1
Target
FUNCTION: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
SUBUNIT: Component of two distinct SNARE complexes consisting of STX5, GOSR2/BOS1, BET1 and SEC22B or STX18, USE1L, BNIP1/SEC20L and SEC22B. YKT6 can probably replace SEC22B in either complex.
SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type IV membrane protein. Golgi apparatus membrane; Single-pass type IV membrane protein. Melanosome.
SUBUNIT: Component of two distinct SNARE complexes consisting of STX5, GOSR2/BOS1, BET1 and SEC22B or STX18, USE1L, BNIP1/SEC20L and SEC22B. YKT6 can probably replace SEC22B in either complex.
SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type IV membrane protein. Golgi apparatus membrane; Single-pass type IV membrane protein. Melanosome.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Mao M, et al. Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998).
2. Nakajima K, et al. EMBO J. 23:3216-3226(2004).
2. Nakajima K, et al. EMBO J. 23:3216-3226(2004).
Limitation
For research use only
Related
products
products
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Code
OSS00048G
$240USD
Unit size
500 µg
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC, WB. A working concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user.
Specificity
Specific for SEC22B.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00048G
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSS00048G
$240USD
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IHC on rat spinal cord using Rabbit antibody to SEC22B (OSS00048G) at a concentration of 30 µg/ml. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown). |
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IHC on rat spinal cord using Rabbit antibody to SEC22B (OSS00048G) at a concentration of 30 µg/ml. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown). |
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IHC on rat brain using Rabbit antibody to SEC22B (OSS00048G) at a concentration of 30 µg/ml. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown). |
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IHC on rat brain using Rabbit antibody to SEC22B (OSS00048G) at a concentration of 30 µg/ml. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown). |
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IHC on rat spinal cord using Rabbit antibody to SEC22B (OSS00048G) at a concentration of 30 µg/ml. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown). |
⚬ Products
Rabbit antibody to SEC22B (2-50)
