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Code
OSS00031W
$240USD
ID Tag
Rb3010-090417-WS
Immunogen
A synthetic peptide from human Syntaxin16 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
STX16, Syn16
Target
FUNCTION: SNARE involved in a vesicular transport step within the Golgi stack.
SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type IV membrane protein.
SUBCELLULAR LOCATION: Isoform C: Cytoplasm.
TISSUE SPECIFICITY: Ubiquitous.
DISEASE: Genetic variations in STX16 may be a cause of pseudohypoparathyroidism type 1B (PHP1B) Pseudohypoparathyroidism refers to a heterogeneous group of disorders characterized by resistance to parathyroid hormone (PTH). PHP1B is characterized by PTH-resistant hypocalcemia and hyperphosphatemia. Patients affected with PHP1B lack developmental defects characteristic of Albright hereditary osteodystrophy, and typically show no other endocrine abnormalities besides resistance to PTH. In some cases microdeletions involving STX16 appear to cause loss of methylation at exon A/B of the GNAS gene, resulting in PHP1B.
SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type IV membrane protein.
SUBCELLULAR LOCATION: Isoform C: Cytoplasm.
TISSUE SPECIFICITY: Ubiquitous.
DISEASE: Genetic variations in STX16 may be a cause of pseudohypoparathyroidism type 1B (PHP1B) Pseudohypoparathyroidism refers to a heterogeneous group of disorders characterized by resistance to parathyroid hormone (PTH). PHP1B is characterized by PTH-resistant hypocalcemia and hyperphosphatemia. Patients affected with PHP1B lack developmental defects characteristic of Albright hereditary osteodystrophy, and typically show no other endocrine abnormalities besides resistance to PTH. In some cases microdeletions involving STX16 appear to cause loss of methylation at exon A/B of the GNAS gene, resulting in PHP1B.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Simonsen A, et al. Eur. J. Cell Biol. 75:223-231(1998).
Limitation
For research use only
Code
OSS00031W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1:500 to 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Syntaxin16.
Spcs X-react.
Human, mouse, rat, marmoset. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00031W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to Syntaxin16
