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Code
OSS00024W
$240USD
ID Tag
Rb320-200308-WS
Immunogen
A synthetic peptide from mouse Synaptotagmin-5 (Synaptotagmin V, SytV, Synaptotagmin IX, Syt5) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Synaptotagmin 5, Synaptotagmin V, SytV, Synaptotagmin IX, Syt5
Target
FUNCTION: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface.
COFACTOR: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.
SUBUNIT: Homodimer. Can also form heterodimers. Interacts with both alpha- and beta-tubulin.
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Note: In mast cells, localizes to the endocytic recycling compartment.
COFACTOR: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.
SUBUNIT: Homodimer. Can also form heterodimers. Interacts with both alpha- and beta-tubulin.
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Note: In mast cells, localizes to the endocytic recycling compartment.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Craxton M.A, et al. FEBS Lett. 361:196-200(1995).
2. Ballif B.A, et al. J. Proteome Res. 7:311-318(2008).
2. Ballif B.A, et al. J. Proteome Res. 7:311-318(2008).
Limitation
For research use only
Code
OSS00024W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for SYT5.
Spcs X-react.
Rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00024W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSS00024W
$240USD
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IF on 1 day- old mouse cortical cell culture using Rabbit antibody to rat, mouse Synaptotagmin-5 (Synaptotagmin V, SytV, Synaptotagmin IX, Syt5): whole serum (OSS00024W) at 1: 2000 dilution. DAPI counter stained. |
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Rabbit antibody to Synaptotagmin 5
