Rb3010-090417-WS

A synthetic peptide from mouse Syntaxin16 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in chicken, orangutan and pig.

Syntaxin 16, STX16, Syn16

FUNCTION: SNARE involved in a vesicular transport step within the Golgi stack.
SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type IV membrane protein.
SUBCELLULAR LOCATION: Isoform C: Cytoplasm.
TISSUE SPECIFICITY: Ubiquitous.
DISEASE: Genetic variations in STX16 may be a cause of pseudohypoparathyroidism type 1B (PHP1B) Pseudohypoparathyroidism refers to a heterogeneous group of disorders characterized by resistance to parathyroid hormone (PTH). PHP1B is characterized by PTH-resistant hypocalcemia and hyperphosphatemia. Patients affected with PHP1B lack developmental defects characteristic of Albright hereditary osteodystrophy, and typically show no other endocrine abnormalities besides resistance to PTH. In some cases microdeletions involving STX16 appear to cause loss of methylation at exon A/B of the GNAS gene, resulting in PHP1B.

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

12 months after reconstitution

This item will be shipped to you at ambient temperature in a lyophilised form.

1. Carninci P, et al. Science 309:1559-1563(2005).

For research use only

100 µl

Unconjugated antibody

NZ white rabbit

Whole serum

Polyclonal

Polyclonal, whole serum

IHC, WB. A dilution of 1 : 500 to 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specific for Syntaxin16.

Mouse. Other species not yet tested.

Lyophilised

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

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