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Code
OSS00013W
$240USD
ID Tag
Rb1712-021210-WS
Immunogen
A synthetic peptide from aa region 60-110 of mouse Syntaxin-1A conjugated to blue carrier protein was used as the antigen.The peptide is homologous in rat and human.
Accession
Also known
Syntaxin-1A, Synaptotagmin-associated 35 kDa protein, P35A, Neuron-specific antigen HPC-1, Sap, Syntaxin 1A; Syntaxin-1B, Stx1b, Stx1b1, Stx1b2
Target
FUNCTION: Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis.
SUBUNIT: Interacts with SYTL4, VAPA and SYBU. Found in a complex with VAMP8 and SNAP23. Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds to CPLX1. Binds STXBP6. Found in a ternary complex with STX1A and SNAP25.
SUBCELLULAR LOCATION: Membrane; Single-pass type IV membrane protein.
TISSUE SPECIFICITY: Expressed predominantly in cerebral cortex, hippocampus, cerebellum, adrenal medulla and retina with weak expression detected in non-neuronal tissues.
SUBUNIT: Interacts with SYTL4, VAPA and SYBU. Found in a complex with VAMP8 and SNAP23. Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds to CPLX1. Binds STXBP6. Found in a ternary complex with STX1A and SNAP25.
SUBCELLULAR LOCATION: Membrane; Single-pass type IV membrane protein.
TISSUE SPECIFICITY: Expressed predominantly in cerebral cortex, hippocampus, cerebellum, adrenal medulla and retina with weak expression detected in non-neuronal tissues.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Inoue A, et al. J. Biol. Chem. 267:10613-10619(1992).
Limitation
For research use only
Code
OSS00013W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Syntaxin-1A & Syntaxin-1B.
Spcs X-react.
Rat, mouse, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00013W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to Syntaxin-1A-1B (60-110)
