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Code
OSS00012W
$240USD
ID Tag
Rb307-200308-WS
Immunogen
A synthetic peptide from n-terminal region of mouse Syntaxin-7 (STX7, Syn7, Syntaxin 7) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Syntaxin-7, STX7, Syn7
Target
FUNCTION: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes.
SUBUNIT: Forms a SNARE complex with VTI1B, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Interacts with VPS33A. Found in a complex with VAMP8 and VTI1B in the liver. Part of the SNARE core complex containing VAMP8, STX8 and VTI1B. Interacts with VPS11, VPS16 and VPS18.
SUBCELLULAR LOCATION: Early endosome membrane; Single-pass type IV membrane protein.
SUBUNIT: Forms a SNARE complex with VTI1B, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Interacts with VPS33A. Found in a complex with VAMP8 and VTI1B in the liver. Part of the SNARE core complex containing VAMP8, STX8 and VTI1B. Interacts with VPS11, VPS16 and VPS18.
SUBCELLULAR LOCATION: Early endosome membrane; Single-pass type IV membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Wong S.H, et al. J. Biol. Chem. 273:375-380(1998).
2. Munton R.P, et al. Mol. Cell. Proteomics 6:283-293(2007).
2. Munton R.P, et al. Mol. Cell. Proteomics 6:283-293(2007).
Limitation
For research use only
Code
OSS00012W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for Syntaxin-7.
Spcs X-react.
Rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00012W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSS00012W
$240USD
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IHC on rat spinal cord (dorsal horn) using Rabbit antibody to n-terminal region of Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum (OSS00012W) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown). |
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IHC on rat trigeminal nerve using Rabbit antibody to n-terminal region of Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum (OSS00012W) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown). |
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IHC on rat spinal cord (central canal) using Rabbit antibody to n-terminal region of Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum (OSS00012W) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown). |
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IF on 1 day- old mouse cortical cell culture using Rabbit antibody to n-terminal region of Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum (OSS00012W) at 1: 2000 dilution. DAPI counter stained. |
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WB on rat brain lysate using Rabbit antibody to n-terminal region of Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum (OSS00012W) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide abolishes the detected band. |
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Rabbit antibody to Syntaxin 7
