⚬ Services
Code
OSC00011G
$260USD    Buy Now 

ID Tag
Sh267-020217-G

Immunogen
A synthetic peptide from human cFos protein conjugated to blue carrier protein has been used as the antigen.

Accession

Also known
Proto-oncogene protein cFOS

Target
FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
SUBUNIT: Heterodimer. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB
SUBCELLULAR LOCATION: Nucleus.
INDUCTION: C-fos expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury.
SIMILARITY: Belongs to the bZIP family. Fos subfamily
SIMILARITY: Contains 1 bZIP domain

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. van Straaten F, et al. Proc. Natl. Acad. Sci. U.S.A. 80:3183-3187(1983).

Limitation
For research use only

Code
OSC00011G
$260USD    Buy Now 

Unit size
500 ug

Conjugate
Unconjugated antibody

Host
Sheep

Purity
IgG

Clonality
Polyclonal

Isotype
IgG

Applications
IHC, WB. Use at a concentration of 10-50 ug/ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for cFos.

Spcs X-react.
Human, rat, mouse, marmoset. Other species not yet tested.

Format
Lyophilised. purified, sterile, irradiated and contain 0.02% benzalkonium chloride

Reconstitution
Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Sheep antibody to cFos
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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