MAP1LC3A antibody, MAP1ALC3 antibody, MAP1A/MAP1B LC3 A antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSM00028W

$240USD

ID Tag

Sh62-270108-WS

Immunogen

A synthetic peptide from human microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A, MAP1A/MAP1B LC3 A) conjugated to an immunogenic carrier protein has been used as the antigen.

Accession

MLP1LC3A_HUMAN
MLP1LC3A_RAT
MLP1LC3A_MOUSE
MAP1LC3A_BOVINE

Also known

MAP1A/MAP1B LC3 A, MAP1A/1B light chain 3 A, MAP1 light chain 3-like protein 1, Microtubule-associated protein 1 light chain 3 alpha, Autophagy-related protein LC3 A Autophagy-related ubiquitin-like modifier LC3 A, MAP1ALC3, MAP1BLC3, MAP1LC3A

Target

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene.
This protein is probably involved in formation of autophagosomal vacuoles.
SUBCELLULAR LOCATION: Cytoplasm. Intracytoplasmic membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note: LC3-II binds to the autophagic membranes.
TISSUE SPECIFICITY: Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Taylor M.P, et al. J. Virol. 81 (22), 12543-12553(2007).

Limitation

For research use only