Code
OSA00043W
$240USD
ID Tag
Sh59-270108-WS
Immunogen
A synthetic peptide from human ATG9B conjugated to an immunogenic carrier protein has been used as the antigen.
Accession
Also known
ATG9B, Autophagy-related protein 9B, APG9-like 2, Nitric oxide synthase 3-overlapping antisense gene protein, Protein sONE, APG9L2, NOS3AS, SONE
Target
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed.
FUNCTION: Plays a role in autophagy.
SUBCELLULAR LOCATION: Cytoplasmic vesicle, autophagosome membrane, Multi-pass membrane protein.
TISSUE SPECIFICITY: Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Fish J.E, et al. J. Biol. Chem. 282:15652-15666(2007).
2. Ota T, et al. Nat. Genet. 36:40-45(2004).
Limitation
For research use only
Code
OSA00043W
$240USD
Unit size
150 µl
Conjugate
Unconjugated antibody
Host
Sheep
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. Use at a dilution of 1 : 200 to 1 : 2000. The optimal dilution should be determined by the end user.
Specificity
Specific for ATG9B.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 150 µl of sterile water. Centrifuge to remove any insoluble material.