Sh3-281007-WS

A synthetic peptide from human microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A, MAP1A/MAP1B LC3 A) conjugated to blue carrier protein has been used as the antigen.

MLP1LC3A_HUMAN
MLP1LC3A_RAT
MLP1LC3A_MOUSE

MAP1A/MAP1B LC3 A, MAP1A/1B light chain 3 A, MAP1 light chain 3-like protein 1, Microtubule-associated protein 1 light chain 3 alpha, Autophagy-related protein LC3 A Autophagy-related ubiquitin-like modifier LC3 A, MAP1ALC3, MAP1BLC3, MAP1LC3A

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene.
This protein is probably involved in formation of autophagosomal vacuoles.
SUBCELLULAR LOCATION: Cytoplasm. Intracytoplasmic membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note: LC3-II binds to the autophagic membranes.
TISSUE SPECIFICITY: Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

12 months after reconstitution

This item will be shipped to you at ambient temperature in a lyophilised form.

1. Taylor M.P, et al. J. Virol. 81 (22), 12543-12553(2007).

For research use only

	Code Product Name OSM00022G Sheep antibody to MAP1LC3A OSM00024W Rabbit antibody to MAP1LC3A OSM00028W Sheep antibody to MAP1LC3A OSM00029W Rabbit antibody to MAP1LC3A

150 ul

Unconjugated antibody

Sheep

Whole serum

Polyclonal

Polyclonal, whole serum

IHC, WB. Use at a dilution of 1 : 200 to 1 : 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specific for MAP1LC3A.

Human, mouse and rat. Other species not yet tested.

Lyophilised

Reconstitute in 150 ul of sterile water. Centrifuge to remove any insoluble material.

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

- Click to download the Data Sheet

- Click to download the Material Safety Data Sheet