Code
OSR00235W
$240USD
ID Tag
Rb242-B2-251107-WS
Immunogen
A synthetic peptide from aa region 200-250 of mouse vomeronasal type-1 receptors B2 and B4 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Vomeronasal receptor VRi2, V1rb2, VN1B2; (see the Immunogen) and VN1B4, vomeronasal type-1 receptor B4, vomeronasal type-1 receptor A10, vomeronasal type-1 receptor B11, V1ra10, V1rb11, V1rb4
Target
FUNCTION: Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in a subset of sensory neurons located in the apical layer of the vomeronasal organ.
MISCELLANEOUS: Mice lacking V1RB2 show a disrupted pattern of axonal projections to the accessory olfactory bulb.
MISCELLANEOUS: Mice lacking all but one V1RA and V1RB gene (12% of the V1R repertoire) show a lack of chemosensory response to a subset of known pheromonal ligands and changes in maternal aggression as well as male reproductive behavior.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Rodriguez I, et al. Cell 97:199-208(1999).
2. Del Punta K, et al. Genome Res. 10:1958-1967(2000).
Limitation
For research use only
Code
OSR00235W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 1000 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for VN1B2 and also VN1B4.
Spcs X-react.
Mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.