TAS2R10 antibody, T2R10 antibody, human taste receptor, type 2, member 10 antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSR00158W

$240USD

ID Tag

Rb186-251107-WS

Immunogen

A synthetic peptide from aa region 200-250 of human TAS2R10 conjugated to blue carrier protein was used as the antigen.

Accession

TAS2R10_HUMAN

Also known

Taste receptor type 2 member 10, T2R10, Taste receptor family B member 2, TRB2

Target

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.
FUNCTION: Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
MISCELLANEOUS: Several bitter taste receptors are expressed in a single taste receptor cell.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Adler E, et al. Cell 100:693-702(2000).

Limitation

For research use only

Code

OSR00158W

$240USD

Unit size

100 ul

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for TAS2R10.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Code

GST00040P

$120USD

ID Tag

41755-30

Unit size

50 Âµg

Accession

TAS2R10_HUMAN

Also known

Taste receptor type 2 member 10, T2R10, Taste receptor family B member 2, TRB2

Target

This is the immunising peptide for the product Rabbit antibody to human taste receptor, type 2, member 10 (TAS2R10, T2R10, TRB2): whole serum (OSR00158W).

Purity

>85%

Applications

Control peptide

Format

Lyophilised

Reconstitution

This peptide is soluble in PBS and water.

Storage

Maintain refrigerated at 2-8°C for up to 12 months. After reconstitution keep at -20°C. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Adler E, et al. Cell 100:693-702(2000).
2. Fischer A, et al. Mol. Biol. Evol. 22:432-436(2005).
3. Hillier L.W, et al. Nature 424:157-164(2003).
4. Chandrashekar J, et al. Cell 100:703-711(2000).
5. Montmayeur J.-P, et al. Curr. Opin. Neurobiol. 12:366-371(2002).
6. Margolskee R.F. J. Biol. Chem. 277:1-4(2002).
7. Zhang Y, et al. Cell 112:293-301(2003).

Limitation

For research use only