Code
OSR00112W
$240USD
ID Tag
Rb150-281007-WS
Immunogen
A synthetic peptide from rat MRGPRD conjugated to blue carrier protein was used as the antigen.
Accession
Also known
MRGPRD, beta-alanine receptor, G-protein coupled receptor TGR7, Mrgd, MAS-related GPR, member D
Target
FUNCTION: May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. The receptor couples with G-protein G(q) and G(i).
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Co-expressed in the small diameter neurons with P2X3 and VR1 in dorsal root ganglia.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Zylka M.J, et al. Proc. Natl. Acad. Sci. U.S.A. 100:10043-10048(2003).
2. Shinohara T, et al. J. Biol. Chem. 279:23559-23564(2004).
Limitation
For research use only
Code
OSR00112W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for MRGPRD.
Spcs X-react.
Rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.