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Code
OSR00111W
$240USD
ID Tag
Rb149-281007-WS
Immunogen
A synthetic peptide from aa region 250-300 of rat MRGPRA conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Nuclear receptor MrgA10 RF-amide G protein-coupled receptor, Mrga10, MrgA, Mrgpra, MGC108580
Target
FUNCTION: Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Bender E, et al. Proc. Natl. Acad. Sci. U.S.A. 99:8573-8578(2002).
Limitation
For research use only
Code
OSR00111W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 4000 for WB on rat lysates is recommended and for mouse tissue lysates 1 : 2000 i; 1:1000 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for MRGPRA.
Spcs X-react.
Rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
- Click to see the eLab Book
Code
OSR00111W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSR00111W
$240USD
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WB on mouse/rat tissue lysates. Blocking: 1% LFDM for 30 min at RT; primary antibody dilution for rat lysates: dilution 1:4000 and for mouse lysates: 1:2000 incubated at 4C overnight. Click on eLAB BOOK tab to see the details. |
⚬ Products
Rabbit antibody to MRGPRA (250-300)
