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Code
OSR00109W
$260USD    Buy Now 

ID Tag
Rb147-281007-WS

Immunogen
A synthetic peptide from human Mas-related G-protein coupled receptor member X1, X3 and X4 (MRGPRX1, MRGPRX3, MRGPRX4) conjugated to blue carrier protein was used as the antigen.

Accession

Also known
Mas-related G-protein coupled receptor member X1, X3, X4; Sensory neuron-specific G-protein coupled receptor 3/4, MRGX1, SNSR3, SNSR4, GPCR, MAS-related GPR, member X1, MRGX3, SNSR1, SNSR2, Sensory neuron-specific G-protein coupled receptor 1/2, Sensory neuron-specific G-protein coupled receptor 5/6, MRGX4, SNSR5, SNSR6, MAS-related GPR, member X3; MRGPRX4, MRGPRX3, MRGPRX1

Target
FUNCTION: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Dong X, et al. Cell 106:619-632(2001).

Limitation
For research use only

Code
OSR00109W
$260USD    Buy Now 

Unit size
100 ul

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for MRGPRX1, 3 and 4.

Spcs X-react.
Human. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Rabbit antibody to MRGPRX1, 3, 4
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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