Code
OSA00295W
$260USD
ID Tag
Gp2988-06112023-WS
Immunogen
A synthetic peptide from rat AATC conjugated to blue carrier protein was used as the antigen.
Accession
Also known
AATC, Cysteine aminotransferase, Cysteine transaminase, Glutamate oxaloacetate transaminase 1, Transaminase A
Target
Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Edward L Huttlin et al. Cell. 2010 Dec 23;143(7):1174-89
Limitation
For research use only
Related
products
Code
OSA00295W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
Guinea pig
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 500 is recommended for IHC-P and WB. The optimal dilution should be determined by the end user.
Specificity
Specific for AATC
Spcs X-react.
Rat, mouse, human
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.