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Code
OSV00109W
$260USD
ID Tag
Gp0404-140620-WS
Immunogen
A synthetic peptide to n-terminal region of human VGluT3 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Vesicular glutamate transporter 3, Solute carrier family 17 member 8
Target
FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Defects in SLC17A8 are the cause of non-syndromic sensorineural deafness autosomal dominant type 25 (DFNA25). DFNA25 is a form of sensorineural hearing loss. The expression of DFNA25 deafness is variable in terms of onset and rate of progression, with an age-dependent penetrance resembling an early-onset presbycusis, or senile deafness, a progressive bilateral loss of hearing that occurs in the aged.
SUBCELLULAR LOCATION: Cytoplasmic vesicle ⺠secretory vesicle ⺠synaptic vesicle membrane. Membrane; Multi-pass membrane protein. Cell junction ⺠synapse ⺠synaptosome
TISSUE SPECIFICITY: Expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord and thalamus.
SUBCELLULAR LOCATION: Cytoplasmic vesicle ⺠secretory vesicle ⺠synaptic vesicle membrane. Membrane; Multi-pass membrane protein. Cell junction ⺠synapse ⺠synaptosome
TISSUE SPECIFICITY: Expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord and thalamus.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Takamori S, et al. EMBO Rep. 3:798-803(2002)
Limitation
For research use only
Related
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Code
OSV00109W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
Guinea pig
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 500 is recommended for WB and 1:250 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for VGLUT3.
Spcs X-react.
Human, rat, mouse, marmoset. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
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Code
OSV00109W
$260USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Guinea pig antibody to VGluT3
