Code
OSP00188W
$260USD
ID Tag
Rb2450-081014-WS
Immunogen
A synthetic peptide from human Pallidin conjugated to blue carrier protein was used as the antigen. The peptide shares 95% identity with rat and mouse sequences.
Accession
Also known
BLOC1S6, Pallidin, Syntaxin 13-interacting protein, Biogenesis of lysosome related organelles complex 1 subunit 6
Target
FUNCTION: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.
SUBCELLULAR LOCATION: Cytoplasm. Endomembrane system; Peripheral membrane protein
Note: It can exist as a soluble protein as well as a peripheral membrane protein.
Tissue specificity: Widely expressed.
Blast it
Huang L., et al. J. Nat. Genet. 23:329-332(1999)
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Huang L., et al. J. Nat. Genet. 23:329-332(1999)
Limitation
For research use only
Code
OSP00188W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 100 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for Pallidin.
Spcs X-react.
Human, mouse. Other species not yet tested but expected to work in rat.
Blast it
Huang L., et al. J. Nat. Genet. 23:329-332(1999)
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.