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Code
OST00457W
$240USD
ID Tag
Rb2378-170614-WS
Immunogen
A synthetic peptide from human TAS2R46 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Taste receptor type 2 member 46, T2R46, T2R54, TAS2R54
Target
FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. Cell projection ⺠cilium membrane
Note: In airway epithelial cells, localizes to motile cilia.
TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed on ciliated airway epithelium.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. Cell projection ⺠cilium membrane
Note: In airway epithelial cells, localizes to motile cilia.
TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed on ciliated airway epithelium.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Fischer A, et al. Mol. Biol. Evol. 22:432-436(2005).
Limitation
For research use only
Code
OST00457W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for TAS2R46.
Spcs X-react.
Human, rat, mouse, marmoset. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OST00457W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to TAS2R46
