Code
OSG00104W
$240USD
ID Tag
Rb2339-290414-WS
Immunogen
A synthetic peptide from aa region 280-330 of mouse GGA1 conjugated to blue carrier protein was used as the antigen. The peptide shares 95% identity with human sequence.
Accession
Also known
ADP-ribosylation factor-binding protein GGA1; Golgi-localized, gamma ear-containing, ARF-binding protein 1; Gamma-adaptin-related protein 1
Target
FUNCTION: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
TISSUE SPECIFICITY: Ubiquitously expressed.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Boman A.L, et al. Mol. Biol. Cell 11:1241-1255(2000).
Limitation
For research use only
Code
OSG00104W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Specificity
Specific for GGA1.
Spcs X-react.
Mouse, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.