Code
OSF00027W
$240USD
ID Tag
Rb2280-150114-WS
Immunogen
A synthetic peptide from aa region 310-362 of mouse FPR1 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
fMet-Leu-Phe receptor, fMLP receptor, N-formyl peptide receptor, FPR, N formylpeptide chemoattractant receptor
Target
FUNCTION: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
TISSUE SPECIFICITY: Neutrophils
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Gao J.-L, et al. J. Biol. Chem. 268:25395-25401(1993)
Limitation
For research use only
Code
OSF00027W
$240USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for FPR1.
Spcs X-react.
Mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.