MC2R antibody, Melanocortin receptor 2 antibody, ACTHR antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSM00136W

$240USD

ID Tag

Rb2267-271213-WS

Immunogen

A synthetic peptide from aa region 60-110 of extracellular domain of human MC2R conjugated to blue carrier protein was used as the antigen. The peptide shares 85% identity with mouse sequence.

Accession

MC2R_HUMAN
MC2R_MOUSE

Also known

Adrenocorticotropic hormone receptor, ACTH receptor, ACTH-R, Adrenocorticotropin receptor, Melanocortin receptor 2, MC2-R, ACTHR

Target

Function: Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP).
Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Melanocytes and corticoadrenal tissue.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Ishii T, et al. Clin. Endocrinol. (Oxf.) 53:389-392(2000)

Limitation

For research use only

Code

OSM00136W

$240USD

Unit size

100 ul

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Specificity

Specific for MC2R.

Spcs X-react.

Human. Other species not yet tested but expected to work in mouse.

Format

Lyophilised

Reconstitution

Reconstitute in 100 ul of MQ water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSM00136W