⚬ Services
Code
OSM00135W
$240USD    Buy Now 

ID Tag
Rb2266-271213-WS

Immunogen
A synthetic peptide from aa region 2-45 of extracellular domain of human MC4R conjugated to blue carrier protein was used as the antigen. The peptide shares 89% identity with mouse sequence.

Accession

Also known
Melanocortin receptor 4, MC4-R

Target
Function: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Brain, placental, and gut tissues.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Valli-Jaakola K, et al. J. Clin. Endocrinol. Metab. 89:940-945(2004)

Limitation
For research use only

Related
products

Code
OSM00135W
$240USD    Buy Now 

Unit size
100 µl

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Specificity
Specific for MC4R.

Spcs X-react.
Human. Other species not yet tested but expected to work in mouse.

Format
Lyophilised

Reconstitution
Reconstitute in 100 µl of MQ water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Rabbit antibody to extracellular MC4R (2-45)
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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