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Code
OSM00131W
$240USD
ID Tag
Rb2258-271213-WS
Immunogen
A synthetic peptide from aa region 185-232 of human MIXL1 conjugated to blue carrier protein was used as the antigen. The peptide shares 94% identity with mouse sequence.
Accession
Also known
Homeobox protein MIXL1, Homeodomain protein MIX, MIX1 homeobox like protein 1, Mix.1 homeobox-like protein, MIXL
Target
Function: Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression.
SUBCELLULAR LOCATION: Nucleus.
Tissue specificity: Restricted to progenitors and secondary lymph tissues. In normal hematopoiesis, it is restricted to immature B- and T-lymphoid cells. Present in differentiating embryonic stem cells (at protein level).
SUBCELLULAR LOCATION: Nucleus.
Tissue specificity: Restricted to progenitors and secondary lymph tissues. In normal hematopoiesis, it is restricted to immature B- and T-lymphoid cells. Present in differentiating embryonic stem cells (at protein level).
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Mossman A.K, et al. Stem Cells Dev. 14:656-663(2005)
Limitation
For research use only
Related
products
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Code
OSM00131W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for MIXL1.
Spcs X-react.
Human. Other species not yet tested but expected to work in mouse.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSM00131W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to MIXL1 (185-232)
