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Code
OSA00257W
$240USD
ID Tag
Rb2239-201113-WS
Immunogen
A synthetic peptide from aa region 650-700 of human ABCC7 conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 93% identity with rat sequence.
Accession
Also known
Cystic fibrosis transmembrane conductance regulator, Channel conductance-controlling ATPase, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7, CFTR
Target
FUNCTION: Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Defects in CFTR are the cause of congenital bilateral absence of the vas deferens (CBAVD). CBAVD is an important cause of sterility in men and could represent an incomplete form of cystic fibrosis, as the majority of men suffering from cystic fibrosis lack the vas deferens.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Found on the surface of the epithelial cells that line the lungs and other organs.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Found on the surface of the epithelial cells that line the lungs and other organs.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Riordan J.R, et al. Science 245:1066-1073(1989)
Limitation
For research use only
Related
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Code
OSA00257W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for ABCC7.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSA00257W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to ABCC7 (CFTR, 650-700)
