Code
OSA00249W
$240USD
ID Tag
Rb2227-201113-WS
Immunogen
A synthetic peptide from aa region 280-330 of human ABCC1 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Multidrug resistance associated protein 1, ATP binding cassette sub family C member 1, Leukotriene C(4) transporter, LTC4 transporter, MRP, MRP1
Target
FUNCTION: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Subcellular location: Cell membrane; Multi-pass membrane protein
Tissue specificity: Lung, testis and peripheral blood mononuclear cells.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Robbiani D.F, et al. Cell 103:757-768(2000)
Limitation
For research use only
Related
products
Code
OSA00249W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for ABCC1.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.