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Code
OSR00059W
$240USD
ID Tag
Rb2515-140415-WS
Immunogen
A synthetic peptide from mouse TRPV5 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat.
The location of the epitope is highlighted in green.
The location of the epitope is highlighted in green.
Accession
Also known
Transient receptor potential cation channel subfamily V member 5, osm-9-like TRP channel 3, OTRPC3, Epithelial calcium channel 1, ECaC1, Calcium transporter 2, CaT2, Ecac,CAT2, ECAC1
Target
FUNCTION: Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
SUBCELLULAR LOCATION: Apical cell membrane; Multi-pass membrane protein. Note=Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells.
SUBCELLULAR LOCATION: Apical cell membrane; Multi-pass membrane protein. Note=Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Carninci P, et al. Science 309:1559-1563(2005).
2. van de Graaf S.F.J, et al. J. Am. Soc. Nephrol. 17:26-30(2006).
2. van de Graaf S.F.J, et al. J. Am. Soc. Nephrol. 17:26-30(2006).
Limitation
For research use only
Code
OSR00059W
$240USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 1000 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for TRPV5.
Spcs X-react.
Mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSR00059W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to TRPV5
