Code
OSS00394W
$240USD
ID Tag
Rb2203-201113-WS
Immunogen
A synthetic peptide from aa region of 300-350 of human SLC9A3 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse and rat.
Accession
Also known
SL9A3, Sodium/hydrogen exchanger 3, Na(+)/H(+) exchanger 3, NHE-3, Solute carrier family 9 member 3, NHE3
Target
FUNCTION: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Tissue specificity: Most abundant in colon and small intestine, followed by kidney and stomach.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. Note: In intestinal epithelial cells, localizes to the ileal brush border
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Brant S.R, et al. Am. J. Physiol. 269:C198-C206(1995)
2. Schmutz J, et al. Nature 431:268-274(2004)
Limitation
For research use only
Related
products
Code
OSS00394W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SLC9A3.
Spcs X-react.
Human, mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.