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Code
OSR00058W
$240USD
ID Tag
Rb1617-211110-WS
Immunogen
A synthetic peptide from 1t extracellular domain of rat TRPV5 conjugated to an immunogenic carrier protein was used as the antigen.
The location of the epitope is highlighted in green.
The location of the epitope is highlighted in green.
Accession
Also known
Transient receptor potential cation channel subfamily V member 5, TrpV5, osm-9-like TRP channel 3, OTRPC3, Epithelial calcium channel 1, ECaC1, Calcium transporter 2, CaT2, Ecac
Target
FUNCTION: Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating .
SUBCELLULAR LOCATION: Apical cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Exclusively expressed in kidney.
SUBCELLULAR LOCATION: Apical cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Exclusively expressed in kidney.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Peng J.-B, et al. J. Biol. Chem. 275:28186-28194(2000).
2. van Abel,M, et al. Kidney Int. 68 (4), 1708-1721 (2005).
2. van Abel,M, et al. Kidney Int. 68 (4), 1708-1721 (2005).
Limitation
For research use only
Related
products
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Code
OSR00058W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for TRPV5.
Spcs X-react.
Rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSR00058W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to TRPV5
