Code
OSL00025W
$240USD
ID Tag
Rb2200-011013-WS
Immunogen
A synthetic peptide from aa region 450-500 of human LRRC4 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 97% identity with rat and mouse sequences.
Accession
Also known
Leucine-rich repeat-containing protein 4, Brain tumor-associated protein BAG, Nasopharyngeal carcinoma-associated gene 14 protein, Netrin-G2 ligand, NGL-2, BAG
Target
Function: Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma.
Subcellular location: Membrane; Single-pass type I membrane protein. Cell junction ⺠synapse ⺠postsynaptic cell membrane. Note: LRRC4 and DLG4 are interdependent for synaptic localization
Tissue specificity: Specifically expressed in brain.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Zhang Q, et al. FEBS Lett. 579:3674-3682(2005)
Limitation
For research use only
Code
OSL00025W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for LRRC4.
Spcs X-react.
Human. Other species not yet tested but likely to work in rat and mouse.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.