Code
OSM00128W
$240USD
ID Tag
Rb2198-011013-WS
Immunogen
A synthetic peptide from aa region 450-500 of human MPP8 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
M phase phosphoprotein 8, Two hybrid associated protein 3 with RanBPM, Twa3, MPHOSPH8
Target
Function: Involved in transcriptional regulation. Specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression.
Subcellular location: Nucleus. Note: Detected on heterochromatin. Detected on nucleosomes.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Matsumoto-Taniura N, et al. Mol. Biol. Cell 7:1455-1469(1996)
Limitation
For research use only
Code
OSM00128W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for MPP8.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.