Code
OSN00094W
$240USD
ID Tag
Rb2166-011013-WS
Immunogen
A synthetic peptide from aa region 290-340 of mouse NBR1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and shares 98% identity with human sequence.
Accession
Also known
Next to BRCA1 gene 1 protein, Cell migration-inducing gene 19 protein, Membrane component chromosome 17 surface marker 2, Neighbor of BRCA1 gene 1 protein, Protein 1A1-3B
Target
Function: Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.
Subcellular location: Cytoplasm, Cytoplasmic vesicle ⺠autophagosome. Lysosome. Cytoplasm ⺠myofibril ⺠sarcomere ⺠M line. Note: In cardiac muscles localizes to the sarcomeric M line. Is targeted to lysosomes for degradation.
Tissue specificity: Expressed in brain.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Dimitrov S, et al. Gene 262:89-98(2001)
Limitation
For research use only
Code
OSN00094W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for NBR1
Spcs X-react.
Mouse, rat, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.