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Code
OSF00022W
$240USD
ID Tag
Rb2177-011013-WS
Immunogen
A synthetic peptide from aa region 2-50 of mouse FGF13 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in human and rat.
Accession
Also known
Fibroblast growth factor 13, FGF-13, Fibroblast growth factor homologous factor 2, FHF-2, FHF2
Target
Function: Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus.
May regulate voltage-gated sodium channels transport and function.
May also play a role in MAPK signaling.
Subcellular location: Cell projection ⺠filopodium. Cell projection ⺠growth cone, Cell projection ⺠dendrite. Nucleus
Tissue specificity: Ubiquitously expressed. Predominantly expressed in the nervous system.
May regulate voltage-gated sodium channels transport and function.
May also play a role in MAPK signaling.
Subcellular location: Cell projection ⺠filopodium. Cell projection ⺠growth cone, Cell projection ⺠dendrite. Nucleus
Tissue specificity: Ubiquitously expressed. Predominantly expressed in the nervous system.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Smallwood P.M, et al. Proc. Natl. Acad. Sci. U.S.A. 93:9850-9857(1996)
Limitation
For research use only
Code
OSF00022W
$240USD
Unit size
150 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for FGF13.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 150 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSF00022W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to FGF13 (2-50)
