Code
OSC00312W
$240USD
ID Tag
Rb2148-011013-WS
Immunogen
A synthetic peptide from aa region 2-52 of human CACNG5 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares about 86% identity with mouse's and rat's.
Accession
Also known
Voltage dependent calcium channel gamma 5 subunit, Neuronal voltage gated calcium channel gamma 5 subunit, Transmembrane AMPAR regulatory protein gamma 5, Neuronal voltage gated calcium channel gamma 5 subunit
Target
FUNCTION: Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state.
Subcellular location: Membrane; Multi-pass membrane protein. Cell junction ⺠synapse ⺠postsynaptic cell membrane ⺠postsynaptic density
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Burgess D.L, et al. Genome Res. 9:1204-1213(1999)
2. Ota T, et al. Nat. Genet. 36:40-45(2004)
Limitation
For research use only
Related
products
Code
OSC00312W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for CACNG5.
Spcs X-react.
Human. Other species not yet tested but likely to work in rat and mouse.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.