Code
OSM00115W
$240USD
ID Tag
Rb2124-230713-WS
Immunogen
A synthetic peptide from aa region 500-550 of human MACC1 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Metastasis associated in colon cancer protein 1, SH3 domain containing protein 7a5
Target
Function: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note: Mainly found in the cytoplasm in non-metastasizing tumors.
Tissue specificity: Preferentially expressed in metastasizing tumors.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Stein U, et al. Nat. Med. 15:59-67(2009)
Limitation
For research use only
Code
OSM00115W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for MACC1.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.