Code
OSS00379W
$240USD
ID Tag
Rb2113-230713-WS
Immunogen
A synthetic peptide from aa region 5-50 of human Syntabulin conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Golgi localized syntaphilin related protein, Syntaxin-1-binding protein, SYBU, GOLSYN
Target
FUNCTION: Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone components and contributes to activity-dependent presynaptic assembly during neuronal development.
Subcellular location: Isoform 1: Cytoplasm ⺠cytoskeleton. Cytoplasmic vesicle. Note: Colocalizes with syntaxin vesicles along microtubules in neuronal processes.
Isoform 3: Golgi apparatus membrane; Single-pass membrane protein
Isoform 4: Golgi apparatus membrane; Single-pass membrane protein
Isoform 5: Golgi apparatus membrane; Single-pass membrane protein
Tissue specificity: Isoform 3, isoform 4 and isoform 5 are expressed in HeLa cell line (at protein level). Isoform 3 is expressed in fetal and adult brain. Isoform 4 is expressed in numerous fetal tissues (brain, kidney, liver, lung, and thymus) and in adult brain, kidney, liver, lung, pancreas, colon, prostate, small intestine, testis and thymus. Isoform 5 is expressed in fetal brain, brain and small intestine.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Su Q, et al. Nat. Cell Biol. 6:941-953(2004)
Limitation
For research use only
Code
OSS00379W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Syntabulin.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.