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Code
OSM00114W
$240USD
ID Tag
Rb2090-100613-WS
Immunogen
A synthetic peptide from aa region 100-150 of mouse MANF conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Mesencephalic astrocyte derived neurotrophic factor, Arginine rich protein, Protein ARMET, ARP
Target
FUNCTION: Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Tissue specificity: Strongly expressed in pancreatic islets and spermatocytes (at protein level).
SUBCELLULAR LOCATION: Secreted.
Tissue specificity: Strongly expressed in pancreatic islets and spermatocytes (at protein level).
SUBCELLULAR LOCATION: Secreted.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Petrova P, et al. J. Mol. Neurosci. 20:173-188(2003)
Limitation
For research use only
Related
products
products
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Code
OSM00114W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for MANF.
Spcs X-react.
Human, mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSM00114W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to MANF
