Code
OSC00300W
$240USD
ID Tag
Rb2064-080513-WS
Immunogen
A synthetic peptide from aa region 450-500 of human CRMP1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat, mouse and chicken.
Accession
Also known
Dihydropyrimidinase-related protein 1, DRP-1, Collapsin response mediator protein 1, CRMP-1, Unc-33-like phosphoprotein 3, ULIP-3, DPYSL1, ULIP3
Target
FUNCTION: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm ⺠cytoskeleton ⺠microtubule organizing center ⺠centrosome. Cytoplasm ⺠cytoskeleton ⺠spindle. Note: Associated with centrosomes and the mitotic spindle during metaphase.
TISSUE SPECIFICITY: Brain
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Hamajima N, et al. Gene 180:157-163(1996)
Limitation
For research use only
Code
OSC00300W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for CRMP1.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.