Glutamate receptor 2 antibody, anti GluR-2 antibody, anti GRIA2 antibody, AMPA 2 antibody, GLUR2 antibody, AMPA2 antibody

Primary Antibodies

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSA00236W

$240USD

ID Tag

Rb2011-200213-WS

Immunogen

A synthetic peptide from human AMPA2 conjugated to blue carrier protein was used as the antigen.

Accession

AMPA2_MOUSE
AMPA2_HUMAN
AMPA2_RAT

Also known

GRIA2, Glutamate receptor 2, GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2, GLUR2

Target

FUNCTION: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction âº synapse âº postsynaptic cell membrane; Multi-pass membrane protein.
Tissue specificity: Detected in brain cortex, hippocampus and cerebellum (at protein level). Detected in hippocampus.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Koehler M, et al. J. Biol. Chem. 269:17367-17370(1994)

Limitation

For research use only

Code

OSA00236W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for AMPA2.

Spcs X-react.

Human, mouse, rat. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSA00236W