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Code
OSA00225W
$240USD
ID Tag
Rb1970-091212-WS
Immunogen
A synthetic peptide from aa region 1500-1581 of human ABCC8 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
ATP-binding cassette sub-family C member 8, Sulfonylurea receptor 1, HRINS, SUR, SUR1
Target
FUNCTION: Putative subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K+ channels and insulin release.
Defects in ABCC8 are a cause of leucine-induced hypoglycemia (LIH).
Defects in ABCC8 are a cause of diabetes mellitus permanent neonatal (PNDM).
Defects in ABCC8 are the cause of transient neonatal diabetes mellitus type 2 (TNDM2).
Subcellular location: Membrane; Multi-pass membrane protein.
Defects in ABCC8 are a cause of leucine-induced hypoglycemia (LIH).
Defects in ABCC8 are a cause of diabetes mellitus permanent neonatal (PNDM).
Defects in ABCC8 are the cause of transient neonatal diabetes mellitus type 2 (TNDM2).
Subcellular location: Membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Thomas P.M, et al. Science 268:426-429(1995)
Limitation
For research use only
Code
OSA00225W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for ABCC8.
Spcs X-react.
Human. Other species not yet tested but expected to work in mouse and rat.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSA00225W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to ABCC8
