ABCC8 antibody, SUR1 antibody, SUR antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSA00224W

$260USD

ID Tag

Rb1969-091212-WS

Immunogen

A synthetic peptide from aa region 600-700 of human ABCC8 conjugated to blue carrier protein was used as the antigen.

Accession

ABCC8_HUMAN

Also known

ATP-binding cassette sub-family C member 8, Sulfonylurea receptor 1, HRINS, SUR, SUR1

Target

FUNCTION: Putative subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K⁺ channels and insulin release.
Defects in ABCC8 are a cause of leucine-induced hypoglycemia (LIH).
Defects in ABCC8 are a cause of diabetes mellitus permanent neonatal (PNDM).
Defects in ABCC8 are the cause of transient neonatal diabetes mellitus type 2 (TNDM2).
Subcellular location: Membrane; Multi-pass membrane protein.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Thomas P.M, et al. Science 268:426-429(1995)

Limitation

For research use only

Code

OSA00224W

$260USD

Unit size

100 ul

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for ABCC8.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSA00224W