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Code
OSA00216W
$240USD
ID Tag
Rb1961-091212-WS
Immunogen
A synthetic peptide from aa region 400-500 of mouse ABCB6 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
ATP-binding cassette sub-family B member 6, mitochondrial, Mitochondrial ABC transporter 3, Mt-ABC transporter 3, P-glycoprotein-related protein, Ubiquitously-expressed mammalian ABC half transporter, MTABC3, PRP, UMAT
Target
FUNCTION: Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
Defects in ABCB6 are the cause of microphthalmia, isolated, with coloboma, type 7 (MCOPCB7).
Subcellular location: Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus
Tissue specificity: Widely expressed. High expression is detected in the retinal epithelium.
Defects in ABCB6 are the cause of microphthalmia, isolated, with coloboma, type 7 (MCOPCB7).
Subcellular location: Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus
Tissue specificity: Widely expressed. High expression is detected in the retinal epithelium.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Krishnamurthy P.C, et al. Nature 443:586-589(2006)
Limitation
For research use only
Related
products
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Code
OSA00216W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for ABCB6.
Spcs X-react.
Mouse, rat. Other species not yet tested but likely to work in human.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSA00216W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to ABCB6
