Code
OSA00209W
$240USD
ID Tag
Rb1954-091212-WS
Immunogen
A synthetic peptide from aa region 2350-2400 of human ABCA2 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
ATP-binding cassette sub-family A member 2, ATP-binding cassette transporter 2, ATP-binding cassette 2, ABC2
Target
FUNCTION: Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.
Subcellular location: Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Note: Forms discrete, punctate intracellular vesicles.
Tissue specificity: Highly expressed in the brain, whereas lower levels of expression is observed in kidney and liver.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Kaminski W.E, et al. Biochem. Biophys. Res. Commun. 281:249-258(2001)
2. Olsen J.V, et al. Cell 127:635-648(2006)
Limitation
For research use only
Code
OSA00209W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for ABCA2.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.