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Code
OSN00077W
$240USD
ID Tag
Rb1889-141012-WS
Immunogen
A synthetic peptide from aa region 150-200 of human Neprilysin conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Mel transforming oncogene like 1, MELL1, Membrane metallo endopeptidase like 1, Membrane metallo endopeptidase like 2, MMEL1, MMEL2, NEPII, Neprilysin 2, Neprilysin Like 1, NL1, NL2, SEP, Soluble secreted endopeptidase
Target
FUNCTION: Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond.
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein. Secreted. Note: A secreted form produced by proteollytic cleavage also exists.
TISSUE SPECIFICITY: Predominantly expressed in testis. Weakly expressed in brain, kidney and heart.
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein. Secreted. Note: A secreted form produced by proteollytic cleavage also exists.
TISSUE SPECIFICITY: Predominantly expressed in testis. Weakly expressed in brain, kidney and heart.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Bonvouloir N, et al. DNA Cell Biol. 20:493-498(2001)
Limitation
For research use only
Code
OSN00077W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for NEP1.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSN00077W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to Neprilysin I
