PICALM antibody, CALM antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSP00172W

$240USD

ID Tag

Rb1887-141012-WS

Immunogen

A synthetic peptide from aa region 330-380 of human PICALM conjugated to an immunogenic carrier protein was used as the antigen.

Accession

PICALM_HUMAN
PICALM_RAT
PICALM_MOUSE

Also known

Phosphatidylinositol-binding clathrin assembly protein, Clathrin assembly lymphoid myeloid leukemia protein, CALM, FIT1

Target

FUNCTION: Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction.
Note=A chromosomal aberration involving PICALM is found in diffuse histiocytic lymphomas.
SUBCELLULAR LOCATION: Membrane âº clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle âº clathrin-coated vesicle. Note: Colocalized with clathrin in the Golgi area.
TISSUE SPECIFICITY: Expressed in all tissues examined.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Silliman C.C, et al. Leukemia 12:1404-1410(1998)
2. Tebar F, et al. Mol. Biol. Cell 10:2687-2702(1999)

Limitation

For research use only

Code

OSP00172W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.

Specificity

Specific for PICALM.

Spcs X-react.

Human, rat, mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSP00172W