|
|
Code
OSK00065W
$240USD
ID Tag
Rb1892-141012-WS
Immunogen
A synthetic peptide from aa region 240-300 of human KCNK1 (TWIK-1) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Potassium channel subfamily K member 1, Inward rectifying potassium channel protein TWIK-1
Target
Function: Weak inwardly rectifying potassium channel. Inhibited by quinine, barium, and internal acidification. Activated by protein kinase C.
Tissue specificity: Widely expressed. Highest expression in brain, kidney, thyroid, salivary gland, adrenal gland, prostate, epididymis, uterus, placenta, colon and jejunum. Moderate expression in eyes, pituitary, pancreas, smooth muscle, testis and ovary. Very low levels in lung, aorta, liver, heart, skeletal muscle, thymus and spleen. In the brain, highest expression in cerebellar granule cells, brainstem, hippocampus and cerebral cortex.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Widely expressed. Highest expression in brain, kidney, thyroid, salivary gland, adrenal gland, prostate, epididymis, uterus, placenta, colon and jejunum. Moderate expression in eyes, pituitary, pancreas, smooth muscle, testis and ovary. Very low levels in lung, aorta, liver, heart, skeletal muscle, thymus and spleen. In the brain, highest expression in cerebellar granule cells, brainstem, hippocampus and cerebral cortex.
Subcellular location: Membrane, Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Lesage F, et al. FEBS Lett. 402:28-32(1997)
2. Munton R.P, et al. Mol. Cell. Proteomics 6:283-293(2007)
2. Munton R.P, et al. Mol. Cell. Proteomics 6:283-293(2007)
Limitation
For research use only
Code
OSK00065W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for KCNK1.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSK00065W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to KCNK1
