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Code
OSE00040W
$240USD
ID Tag
Rb1895-201012-WS
Immunogen
A synthetic peptide from aa region 250-350 of mouse encephalopsin conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat.
Accession
Also known
Opsin-3, encephalopsin, panopsin, OPN3, ECPN, opsin 3
Target
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein.
FUNCTION: May play a role in encephalic photoreception.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.
FUNCTION: May play a role in encephalic photoreception.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Blackshaw S, et al. J. Neurosci. 19:3681-3690(1999).
2. Kasper G, et al. Gene 295:27-32(2002).
3. Carninci P, et al. cience 309:1559-1563(2005).
2. Kasper G, et al. Gene 295:27-32(2002).
3. Carninci P, et al. cience 309:1559-1563(2005).
Limitation
For research use only
Code
OSE00040W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for opsin-3.
Spcs X-react.
Mouse. Other species not yet tested but expected to work in rat.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSE00040W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
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Rabbit antibody to Encephalopsin
