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Code
OSS00343W
$240USD
ID Tag
Rb3145-241117-WS
Immunogen
A synthetic peptide from human SLC6A5 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Sodium- and chloride-dependent glycine transporter 2, GlyT-2, GlyT2, Solute carrier family 6 member 5, GLYT2, NET1
Target
FUNCTION: Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses.
Defects in SLC6A5 are the cause of hyperekplexia type 3 (HKPX3)
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein
Tissue specificity: Expressed in medulla, and to a lesser extent in spinal cord and cerebellum.
Defects in SLC6A5 are the cause of hyperekplexia type 3 (HKPX3)
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein
Tissue specificity: Expressed in medulla, and to a lesser extent in spinal cord and cerebellum.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Morrow J.A, et al. FEBS Lett. 439:334-340(1998)
Limitation
For research use only
Code
OSS00343W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SLC6A5.
Spcs X-react.
Human, rat, mouse, marmoset. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00343W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to SLC6A5
